Scientists find a new way to treat certain heart disease

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A study conducted by Osaka University has found that tricaprin, a dietary supplement, can significantly reverse signs of heart disease, specifically in patients with triglyceride deposit cardiomyovasculopathy (TGCV).

This discovery offers potential relief to patients resistant to standard coronary artery disease (CAD) treatments.

Researchers at Osaka University explored the effects of tricaprin, focusing on its efficacy against TGCV, a form of heart disease characterized by triglyceride deposits obstructing coronary arteries due to defective intracellular breakdown of triglycerides in vascular smooth muscle cells.

This type of heart disease is prevalent among diabetic patients and those who have undergone dialysis.

The study reported notable regression of diffuse coronary atherosclerosis in two TGCV patients, who experienced significant symptom relief after incorporating tricaprin into their diet.

This supplement, known for promoting lipid breakdown by heart muscle cells, also led to a considerable decrease in triglyceride accumulation in the heart’s blood vessels.

The outcomes of this study are groundbreaking as they demonstrate the first instance of regression due to increased intracellular triglyceride lipolysis, providing a conceptually new treatment pathway for coronary atherosclerosis.

These findings are crucial, especially for patients who do not respond to existing CAD treatments, broadening the scope for multi-faceted approaches to managing CAD.

Moreover, the success of tricaprin in alleviating symptoms and reducing triglyceride buildup in TGCV patients opens avenues for further research and development of novel therapeutic strategies targeting specific heart disease subtypes and related conditions.

Tricaprin, a commercially available food supplement, has been identified as a potentially revolutionary treatment for patients with triglyceride deposit cardiomyovasculopathy (TGCV), offering a new approach to treat those resistant to standard remedies for coronary artery disease.

This study, led by Ken-ichi Hirano et al, is a substantial step towards developing diversified and more effective treatments for heart diseases, and it is published in the European Heart Journal.

For further insights on heart health, consider exploring studies on the relation between coffee consumption and heart disease prevention and the connections between COVID infection, vaccination, and heart complications.

Also, investigate new methods to decelerate heart aging and the links between common heartburn medications and silent kidney damage.

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